In the fifth inning, the Astros cracked Darvish and Carlos Correa launched a three-run homer to put them ahead.
Yuli Gurriel, Correa, and Gonzalez all had two hits each.
The Braves would make it interesting in the eighth loading the bases, but Will Harris would work out of the jam.
Charlie Morton would make the offenses work hold up but he’d only able to go 5.2 innings.
In the sixth, Tuesday’s hero, Marwin Gonzalez came through again. With a man on, Gonzalez blasted the ball over the centerfield wall to make it 6-1, the offense plated two more runs in the inning.